IHP news 508: infectious diseases & NTDs

By on February 8, 2019

Plos Collection – Epidemiological metrics for the HIV epidemic

https://collections.plos.org/hiv-transmission-benchmarks

Extraordinary progress has been made to halt and reverse the spread of HIV. However, there is still a long way to go to end the epidemic, as called for in the third Sustainable Development Goal. This Special Collection reviews metrics to understand progress in diverse HIV epidemics. It considers both the public health and the human rights lessons learned from other infectious diseases and provides suggestions to evaluate the success of global, national and local HIV responses.”

Make sure you check out one of the latest additions to this Collection:

Plos Med – Setting targets for HIV/AIDS—What lessons can be learned from other disease control programmes?

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002735

In a Collection Review, Richard Hayes and colleagues discuss metrics for assessing progress in control of the HIV/AIDS epidemic in the context of prior disease control programmes. Part of the Epidemiological metrics for the HIV epidemic collection.”

HPW – New Funding Partnership To Develop Innovative Drugs For Leishmaniasis

https://www.healthpolicy-watch.org/new-funding-partnership-to-develop-innovative-drugs-for-leishmaniasis/

Wellcome has committed to provide more than £10 million to the Drugs for Neglected Diseases initiative (DNDi) over three years to develop new oral treatments for leishmaniasis, a devastating parasitic disease that primarily affects some of the world’s poorest people.”

Lancet Infectious Diseases (Feb issue)

https://www.thelancet.com/journals/lanhiv/issue/current

Among others, with this CommentReaching the 90-90-90 target: lessons from HIV self-testing and a Viewpoint already published online before Global PrEP roll-out: recommendations for programmatic success.

Johns Hopkins – To Halt Malaria, More Research Focused on Human Behavior Needed

http://ccp.jhu.edu/2019/01/22/malaria-transmission-research-human-behavior/

Wherever possible, researchers should not just focus on mosquito behavior when working to eliminate malaria, but must also consider how humans behave at night when the risk of being bitten by an infected mosquito is highest, new findings from the Johns Hopkins Center for Communication Programs suggest. A CCP-led review article published in  Malaria Journal last week finds that while there is substantial research into when malaria mosquitoes bite, when they are most active and which species are most likely to spread disease, there is very little that considers the other side of the equation: people. “The neglected piece has really been human behavior,” says CCP’s April Monroe, who works on the VectorWorks project funded by the President’s Malaria Initiative. “There’s been a big focus on mosquito behavior. But you have to look at mosquitoes and people together to really understand what is going on and how to reduce malaria risk.”…”

“…While studies have shown that most people who have nets use them, there are times when malaria mosquitoes are biting when it may not be possible to use a net. This includes while doing household chores and socializing in the evening before bed, as well as during outdoor night-shift jobs, such as providing security or fishing, and while attending community events such as funerals, weddings or religious events which can last throughout the night….”

Nature News – ‘Diet drugs’ suppress mosquitoes’ thirst for blood

https://www.nature.com/articles/d41586-019-00511-4

Method shows promise for disease control, but practical hurdles remain.”

“A hungry mosquito is at best a nuisance; at worst, it is a transmitter of deadly diseases. Now, researchers have discovered a way to stop mosquitoes biting — by using human ‘diet’ drugs to trick them into feeling full. The scientists suggest that the drugs could one day be used to control the spread of diseases. Their results are reported in Cell on 7 February…”

 

Cidrap News – Study: Dengue immunity may have offered protection against Zika in Brazil

http://www.cidrap.umn.edu/news-perspective/2019/02/study-dengue-immunity-may-have-offered-protection-against-zika-brazil

A new study published today in Science shows that prior dengue infection may have protected some Brazilians from severe Zika infections during the 2015-2016 epidemic in the Americas. The study findings could have major implications for both Zika and dengue vaccine developments….”

BMJ Editorial – Making the case: developing innovative adherence solutions for the treatment of tuberculosis

M Verma et al; https://gh.bmj.com/content/4/1/e001323

“…TB treatment is challenging with its prolonged and frequent dosing regimen that may be associated with challenging side effects. While significant work has been done to support adherence among people living with TB who are on treatment—including direct observation of therapy and provision of socioeconomic support—there has been limited focus on translation of how the medications themselves and their administration might be altered to improve adherence….”

 

  • Via STAT news – “Authorities in China are investigating whether more than 12,000 units of a blood plasma product were contaminated with HIV.”    But AP already reportedChina says tests on plasma products negative for HIV”. “ Chinese investigators said Thursday tests on a batch of a plasma product feared to have been contaminated with HIV have turned up negative for the virus that causes AIDS. The result appears to have headed off the possibility of yet another scandal involving medical products in the country. Incidents include the falsifying of production records for rabies vaccines that prompted a nationwide crackdown on the industry and the injecting of other faulty vaccines.”

 

  • Via Global Health Now: Measles is making a global comeback, with several outbreaks in different countries….
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